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Which two routes of entry are likely to be the most important in pesticide exposure?

  1. Ocular and injection

  2. Dermal and inhalation

  3. Gastrointestinal and surface absorption

  4. Respiratory and oral

The correct answer is: Dermal and inhalation

The most important routes of entry for pesticide exposure are dermal and inhalation. Dermal exposure occurs when pesticides come into contact with the skin, which can absorb harmful chemicals, leading to systemic toxicity. This is particularly relevant because the skin is an extensive organ with a large surface area, allowing for significant absorption. Inhalation exposure is equally critical, especially for individuals who apply pesticides or work in environments where aerosolized particles can be present. When pesticides are inhaled, they can rapidly enter the bloodstream and affect internal organs, causing immediate and sometimes severe health effects. Other routes mentioned, such as ocular exposure, while potentially important, do not generally affect as many individuals or lead to systemic issues as dermal and inhalation exposure. Gastrointestinal exposure is less relevant for people who are using pesticides according to label instructions, as ingestion is typically avoided in safe handling practices. Hence, the focus on dermal and inhalation routes reflects the most common and significant risks associated with pesticide exposure.