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What safety factor does the EPA typically use to establish tolerances?

  1. 50 times

  2. 75 times

  3. 100 times

  4. 200 times

The correct answer is: 100 times

The Environmental Protection Agency (EPA) typically uses a safety factor of 100 times when establishing tolerances for pesticide residues on food. This standard is employed to ensure a high level of protection for consumers, particularly sensitive populations such as children and pregnant women. The factor accounts for uncertainties in the data, including variations in exposure levels and the potential for differences in susceptibility among individuals. Using a 100-fold safety factor helps provide a conservative estimate of acceptable exposure, thus allowing for a buffer against potential toxic effects that might not be fully understood in the available research. This approach demonstrates the agency’s commitment to health and safety by prioritizing consumer well-being when setting regulatory limits on pesticide residues. Other potential safety factors, such as 50, 75, or 200, may not represent the standard practice for establishing tolerances under typical circumstances as per the EPA's guidelines. The consensus around the use of a 100-fold safety factor is grounded in both scientific research and regulatory practices aimed at protecting public health.