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What factors affect the toxicity of a pesticide?

  1. Route of entry and environmental conditions

  2. Frequency and duration of exposure

  3. Route of entry, frequency and duration of exposure, and dose received

  4. Type of pesticide and method of application

The correct answer is: Route of entry, frequency and duration of exposure, and dose received

The toxicity of a pesticide is influenced by several key factors that determine how harmful it can be to humans, wildlife, or the environment. One of the most critical components is the route of entry, which refers to how the pesticide gets into an organism, whether through ingestion, inhalation, or dermal exposure. Each route can have different implications for absorption and potential harm. Additionally, the frequency and duration of exposure are crucial because they indicate how often and how long an organism is exposed to the pesticide. Repeated exposure over time can lead to accumulation in the body and increased toxicity, while short-term exposure might be less harmful. Lastly, the dose received plays a significant role in determining the overall toxicity. Higher doses are typically associated with more severe effects, while smaller doses may result in less harm. Therefore, when all these factors—route of entry, frequency and duration of exposure, and the specific dose—are taken together, they create a comprehensive understanding of a pesticide's potential toxicity. Other choices may encompass aspects of pesticide toxicity, but they do not capture the complete range of factors affecting toxicity as thoroughly as this correct answer does. Factors such as environmental conditions, type of pesticide, or method of application impact toxicity, but they do not fully encompass the